Poly ADP-Ribose Polymerase (PARP) Inhibitor Global Market By Drug Type, By Application, By Distribution Channel, By Regional Forecast 2024-2033
Overview and Scope
Poly ADP-ribose polymerase (PARP) inhibitors are a class of pharmacological
inhibitors that block the enzyme PARP, which is involved in deoxyribonucleic
acid (DNA) repair. These inhibitors treat cancers with defects in other DNA
repair pathways, preventing cancer cells from repairing damaged DNA and leading
to their death.
Sizing and Forecast
The poly ADP-ribose polymerase (PARP) inhibitor market size has grown rapidly
in recent years. It will grow from 7.52 billion in 2023 to $8.39 billion in
2024 at a compound annual growth rate (CAGR) of 11.6%. The growth in the historic period can be
attributed to clinical research, regulatory approvals, market competition, drug
combinations, and patient advocacy.
The poly ADP-ribose polymerase (PARP) inhibitor market size is expected to see
rapid growth in the next few years. It will grow to $13.13 billion in 2028 at a
compound annual growth rate (CAGR) of 11.8%.
The growth in the forecast period can be attributed to expanded
indications, personalized medicine, biomarker development, health economics,
and emerging markets. Major trends in the forecast period include precision
medicine, immunotherapy advancements, targeted therapies, artificial
intelligence in drug discovery, and patient-centric healthcare.
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Segmentation & Regional Insights
The poly ADP-ribose polymerase (PARP) inhibitor market covered in this report
is segmented –
1) By Drug Type: Talazoparib, Veliparib, Olaparib, Other Drug Types
2) By Distribution Channel: Hospital Pharmacy, Online Pharmacy, Retail
Pharmacy, Other Distribution Channels
3) By Application: Ovarian Cancer, Breast Cancer, Other Applications
4) By End Users: Hospitals, Homecare, Specialty Clinics, Other End Users
North America was the largest region in the poly ADP-ribose polymerase (PARP)
inhibitor market in 2023. Asia-Pacific is expected to be the fastest-growing
region in the forecast period. The regions covered in the Poly ADP-ribose
polymerase (PARP) inhibitor market report are Asia-Pacific, Western Europe,
Eastern Europe, North America, South America, Middle East, Africa.
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Major Driver Impacting Market Growth
The increasing prevalence of ovarian cancer is expected to propel the growth of
the poly ADP-ribose polymerase (PARP) inhibitor market going forward. Ovarian
cancer refers to a malignant tumor that develops in one or both of a woman's
ovaries, which are part of the female reproductive system responsible for
producing eggs and female hormones. Ovarian cancer is growing due to impact of
genetic predisposition, an aging population, environmental exposures, and
hormonal imbalances. Poly ADP-Ribose Polymerase (PARP) Inhibitors are used in
ovarian cancer treatment to target DNA repair mechanisms, specifically in
patients with BRCA mutations, leading to synthetic lethality and enhanced tumor
cell death. For instance, in February 2022, according to the World Ovarian
Cancer Coalition, a Canada-based non-profit organization, ovarian cancer
impacted 3.13 million women globally in 2020, and it's projected to rise by 42%
to reach 4.4 million by 2040. Further, over the same period, there's expected
to be a 51% surge in ovarian cancer-related deaths, climbing from 2.07 in 2020
to 3.13 in 2040. Therefore, the increasing prevalence of ovarian cancer is
driving the growth of the poly ADP-ribose polymerase (PARP) inhibitor market.
Key Industry Players
Major companies operating in the Poly ADP-ribose polymerase (PARP) inhibitor
market are Pfizer Inc., Johnson &
Johnson Services Inc., AbbVie Inc., Bayer AG, Novartis AG, Sanofi S.A.,
AstraZeneca plc, GlaxoSmithKline plc., Takeda Pharmaceutical Company Limited,
Merck KGaA, Teva Pharmaceutical Industries Ltd., Daiichi Sankyo Company
Limited, Eisai Co. Ltd., Ipsen Biopharmaceuticals Inc., Genentech Inc.,
BioMarin Pharmaceutical Inc., Seattle Genetics Inc., Medivation Inc., Myriad
Genetics Inc., PharmaMar S.A., Clovis Oncology, Nektar Therapeutics, Loxo
Oncology Inc., Tolero Pharmaceuticals Inc., Everest Pharmaceuticals, Verastem
Inc
The poly adp-ribose polymerase (parp) inhibitor market report table of
contents includes:
1. Executive Summary
2. Poly ADP-Ribose Polymerase (PARP) Inhibitor Market
Characteristics
3. Poly ADP-Ribose Polymerase (PARP) Inhibitor Market Trends And
Strategies
4. Poly ADP-Ribose Polymerase (PARP) Inhibitor Market - Macro
Economic Scenario
5. Global Poly ADP-Ribose Polymerase (PARP) Inhibitor Market Size
and Growth
.....
32. Global Poly ADP-Ribose Polymerase (PARP) Inhibitor Market
Competitive Benchmarking
33. Global Poly ADP-Ribose Polymerase (PARP) Inhibitor Market
Competitive Dashboard
34. Key Mergers And Acquisitions In The Poly ADP-Ribose Polymerase
(PARP) Inhibitor Market
35. Poly ADP-Ribose Polymerase (PARP) Inhibitor Market Future
Outlook and Potential Analysis
36. Appendix
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