2025 Strategic Guide to the Vaccine Contract Manufacturing Market – Forecasts and Business Use Cases

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What is the projected market size of the vaccine contract manufacturing industry, and what is its expected CAGR?
The vaccine contract manufacturing market size has grown strongly in recent years. It will grow from $3.58 billion in 2024 to $3.93 billion in 2025 at a compound annual growth rate (CAGR) of 9.7%. The growth in the historic period can be attributed to traditional vaccine manufacturing limitations, global disease outbreaks driving vaccine demand, regulatory support for contract manufacturing, increasing complexity of vaccine production, and surge in vaccine research and development

The vaccine contract manufacturing market size is expected to see rapid growth in the next few years. It will grow to $5.93 billion in 2029 at a compound annual growth rate (CAGR) of 10.8%. The growth in the forecast period can be attributed to growing emphasis on pandemic preparedness, increased outsourcing in pharmaceutical manufacturing, expansion of biopharmaceutical companies, accelerated vaccine development timelines, global initiatives for vaccine accessibility. Major trends in the forecast period include integration of single-use technologies in manufacturing, rise in personalized medicine approaches to vaccine development, development of mRNA and viral vector vaccines, adoption of continuous manufacturing processes, expansion of fill-finish services.

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What external factors are influencing the vaccine contract manufacturing market’s growth momentum?
An increase in initiatives favoring vaccinations is expected to propel the growth of the vaccine contract manufacturing market going forward. Vaccination refers to an easy, safe, and efficient method of defending against contagious diseases before they occur. It boosts the immune system and builds up the body's defenses against infections. Increasing initiatives favoring vaccinations would help advance and develop various vaccine manufacturing processes to support vaccine contract manufacturing. For instance, in November 2022, the U.S. Department of Health and Human Services, a US-based cabinet-level executive branch department of the federal government, announced a new $350 million initiative for HRSA (Health Resources and Services Administration)-supported health facilities to boost the number of COVID-19 vaccines in their communities, with an emphasis on marginalized people. Therefore, the increase in initiatives favoring vaccinations is driving the growth of the vaccine contract manufacturing market.

What are the major market segments driving the growth of the vaccine contract manufacturing industry?
The vaccine contract manufacturing market covered in this report is segmented –

1) By Service Type: Fill-Finish, Bulk Product
2) By Vaccine Type: Inactivated Vaccines, Live-Attenuated Vaccines, RNA (Ribonucleic Acid) Vaccines, Subunit Vaccines, Toxoid-Based Vaccines
3) By Process: Downstream, Upstream
4) By Scale Of Operation: Preclinical, Clinical, Commercial
5) By End-Use: Human Use, Veterinary

Subsegments:
1) By Fill-Finish: Aseptic Fill-Finish, Lyophilization, Vial Filling, Syringe Filling
2) By Bulk Product: Cell Culture, Microbial Fermentation, Antigen Production, Buffer Preparation


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What future trends will impact the direction of the vaccine contract manufacturing industry?
Strategic partnerships are a key trend gaining popularity in the vaccine contract manufacturing market. Significant companies are partnering with the companies operating in the vaccine contract manufacturing market to sustain their position in the market. For instance, in January 2023, Vaxxas, an Australia-based biotechnology company that develops a novel needle-free vaccination technology, partnered with the Coalition for Epidemic Preparedness Innovations, a Norway-based foundation, to finance and coordinate the development of new vaccines and promote the development of Vaxxas' needle-free vaccine patch delivery technology in a project that may eliminate the frozen storage requirement for mRNA vaccines. Furthermore, In October 2024, LenioBio, a Germany-based Biotech company, partnered with ReciBioPharm, a US-based contract development and manufacturing organization (CDMO), to scale up its protein manufacturing capabilities and accelerate vaccine production. This partnership aligns with LenioBio’s strategy to expand the scope of its CEPI-funded project, which aims to demonstrate the speed and efficiency of its proprietary ALiCE protein expression technology in producing vaccine-related proteins for use in clinical trials.

Who are the key market players contributing to the growth of the vaccine contract manufacturing industry?
Major companies operating in the vaccine contract manufacturing market include Pfizer Inc, Johnson & Johnson, AbbVie Inc., Sanofi, GlaxoSmithKline, Merck KGaA, Fujifilm Holdings Corporation, Moderna, BioNTech, GSK Vaccines, AstraZeneca PLC, Ajinomoto Co. Inc., Icon plc, Lonza Group AG, Cytiva, Catalent Inc., Charles River Laboratories International Inc., Serum Institute of India Pvt. Ltd, Samsung Biologics, WuXi Biologics, Novavax, Sinovac Biotech, Emergent BioSolutions Inc., Albany Molecular Research Inc., Soligenix Inc., Bio Farma, Curia Global Inc., Hualan Biological Engineering, BioMARC, Bavarian Nordic A/S, AGC Biologics, IDT Biologika GmbH, Bharat Biotech, Goodwin Biotechnology Inc., Biofabri S.L

Which regions are leading the growth of the vaccine contract manufacturing market globally?
North America was the largest region in the vaccine contract manufacturing market in 2024. Asia-Pacific is expected to be the fastest-growing region in the vaccine contract manufacturing market report forecast period. The regions covered in the vaccine contract manufacturing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

How Can Companies Use The Vaccine Contract Manufacturing Market Report to Drive Business Results?
This report provides actionable insights tailored for business use—not academic analysis. Companies can leverage the data to:
• Time market entry or expansion using growth forecasts and CAGR trends.
• Develop competitive products by tracking key technology shifts and user preferences.
• Tailor regional strategies with in-depth geographic data and local market dynamics.
• Benchmark and plan partnerships using competitive landscape insights.

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